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Abstract
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Early detection of breast cancer is crucial in treating this disease. In this article, an approach using
phononic crystal configuration for breast cancer detection through human serum is presented. The proposed
sensor structure consists of a two-dimensional phononic crystal. The crystal is made of PMMA as the host
material and an arrangement of square array of tungsten cylindrical columns. The design includes a straight
waveguide in which five empty columns are embedded in the middle of the waveguide, once filled with
serum from a healthy individual and in the other case filled with serum from an individual with breast
cancer. The results show that the output frequency location has significant shifts in the two displacement
states. In the proposed sensor, the average quality factor is 12523. Additionally, the average sensitivity and
merit factor are Hz.s/m 1137 and 19, respectively. This sensor can demonstrate the initial capability of
detecting changes caused by breast cancer in the serum of a patient
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