مشخصات پژوهش

The objective of this study was to investigate the antifungal susceptibility of oral Candida albicans (C. albicans) strains isolated from HIV+ patients. A total of 50 C. albicans isolates were cultured on Sabouraud glucose agar (SGA) containing chloramohenicol. The antifungal susceptibility of C. albicans against fluconazole, clotrimazole, nystatin, amphotericin B, ketoconazole and flucytosine was assessed using disc diffusion method. The inhibition zones ranged from 4±1.8 to 40±3.8 mm for fluconazole, 7±1.0 to 37±1.8 mm for ketoconazole, 14±0.8 to24±0.8 mm for amphotericin B, 25±0.0 to 33±0.0 mm for nystatin and 7±4.2 to 40±0.0 mm for clotrimazole. We concluded that C. albicans strains from HIV+ patients were resistant to flucytosin and susceptible to nystatin.